The Translational Efficacy Gap
Why interventions extending murine lifespan by 20%+ frequently fail to show significance in Phase II human trials. An analysis of the standard ITP models vs human metabolic realities.
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Clinical trial tracking, biomarker validation, and meta-analyses of geroprotective interventions.
Validated Longevity Biomarkers
A definitive list of the 14 clinical biomarkers most strongly correlated with reduced all-cause mortality and delayed biological aging, including target ranges for optimization.
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